Wine Therapy (nice name)
171 Elizabeth Street (@ Spring Street)
This is a tiny little space in NoLIta that sells wines from lesser known producers and countries (like Lebanon!), and some organic wines as well.
Le Dû's Wines
600 Washington Street (@ Morton Street)
Owned by Jean-Luc Le Dû, previously the sommelier at Daniel, Le Dû's, is a largish shop with about 600 labels, many from small artisanal producers. He also sells sake. An inquiry about the shop was recently posted on Chowhound. One respondent commented, "you may not find yellowtail here, thank goodness!"