The serrations on a bread knife or the slanted bevel on a Japanese-style knife are intended to work with the natural angle of your hand to give you a straighter, smoother cut. If you're a leftie using a right-handed blade, that means you have to work doubly hard to keep your slices straight.
European-style knives are more tailored to use by both lefties or righties. These blades are equally angled on either side of the edge, though lefties will still have a hard time with serrated knives.
If you're left-handed and have had trouble finding a knife that feels right in your hand, take a look at some of these leftie knives:
• Shun Classic Left-Handed 8-Inch Chef's Knife, $145 from Amazon.com
• Shun Classic Left-Handed Paring Knife, $80 on Amazon.com
• Messermeister Left-Handed Bread Knife, $85 from Epicurean Edge
• 8-Inch Bread Knife, $23 from Anything Left Handed
Have you ever tried a left-handed knife? Do you think they're worth it?